The NFL releases the schedule for Week 18, with the 49ers and Cardinals playing in the kickoff game.

The San Francisco 49ers' last game of the 2024-25 season is set to take place at a familiar time. They will be facing off against the Arizona Cardinals on Sunday, January 5 at 1:25 p.m. Pacific Time. This will be their ninth afternoon game of the season and will be broadcasted on Fox, KTVU Ch. 2 in the Bay Area.

The NFL announced the schedule for Week 18 on Sunday night, right after the Commanders secured their playoff spot by defeating the Falcons on Sunday Night Football. There will be two games on Saturday, all between AFC North teams, and the remaining 14 games will be played on Sunday.

Unfortunately, the 49ers and the Cardinals will not be playing for a spot in the playoffs as both teams were eliminated last week. The Cardinals emerged victorious in their first meeting this season, pulling off an upset against the Niners with a score of 24-23. This was San Francisco's second loss to a divisional opponent in just 15 days.

The last time the 49ers faced the Cardinals in a season finale was in January 2023, when they dominated with a 38-13 win at home. The last time they ended a season in Arizona was in 2020, when they had to play their final home games at State Farm Stadium due to COVID restrictions in Santa Clara County. Unfortunately, they suffered a 26-23 loss to the Seahawks in a fourth-quarter collapse, with C.J. Beathard as quarterback.

Here is the full schedule for Week 18 as announced by the NFL:

SATURDAY, JAN. 4
1:30 p.m.
Browns at Ravens
5 p.m.
Bengals at Steelers

SUNDAY, JAN. 5
10 a.m.
Commanders at Cowboys
Bears at Packers
Jaguars at Colts
Saints at Buccaneers
Panthers at Falcons
Bills at Patriots
Giants at Eagles
Texans at Titans

1:25 p.m.
49ERS at Cardinals

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Seahawks at Rams
Dolphins at Jets
Chiefs at Broncos
Chargers at Raiders

5:20 p.m.
Vikings at Lions.

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