November 15th 2024.
The wonders of nature never cease to amaze us. When we think of parasitic mushrooms that can turn creatures into zombies, positive thoughts are not the first to come to mind. However, recent studies have shown that the same fungus featured in the popular HBO series, The Last of Us, could potentially be used to treat cancer in a groundbreaking way.
This fungus, known as Cordyceps militaris or caterpillar fungus, is notorious for infecting insect larvae and zombifying them. It feeds on the insect until it dies, and then a mushroom-like stalk sprouts from its head. But what is truly fascinating is the compound produced by this fungus, called cordycepin, which has shown promising effects in stopping the growth of cancer cells.
In a study published in the journal FEBS Letters, scientists from the University of Nottingham investigated the effects of cordycepin on genes inside cells. They found that this compound, when transformed into cordycepin triphosphate, can block two pathways that are often exploited by cancer cells. Although the exact molecules targeted by cordycepin triphosphate are still unknown, it has been found to work quickly and effectively in inhibiting cancer growth.
Cornelia de Moor, a researcher from the School of Pharmacy, stated that "our data confirms that Cordycepin is a good starting point for novel cancer medicines and explains its beneficial effects." This discovery could potentially lead to the development of new and less harmful treatments for cancer patients.
It's worth mentioning that this is not the first time Cordyceps militaris has caught the attention of scientists. In fact, it has been used for centuries in traditional Chinese medicine for its anti-inflammatory and anti-bacterial properties. However, in recent years, the fungus has gained even more recognition due to its appearance in popular culture, most notably in The Last of Us, where a fictional mutated strain of the fungus zombifies humans.
But don't let this sci-fi scenario scare you. Experts assure us that these mushrooms are not a threat to humanity. The mutated version seen in The Last of Us is purely fictional, and the real Cordyceps militaris targets insects like ants. It infects them and releases chemicals that manipulate their behavior until they eventually die, and a stalk grows from their head to release spores.
Although it may seem like something out of a horror movie, this is simply nature's way of survival. And while it may not be pleasant to imagine, it is a reminder of the intricate and fascinating world we live in. So, rest assured, the chances of these mushrooms turning on us are slim to none.
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