A university in NSW claims that a new nasal vaccine for COVID-19 could be a gamechanger.

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There may be a new option for those who are afraid of needles when it comes to getting vaccinated against COVID-19 - through the nose. Researchers from Griffith University in New South Wales have been studying the effectiveness of delivering the coronavirus vaccine through the nasal passages, according to a recent publication in Nature Communications.

This method of delivery is not only being hailed as a gamechanger for administering the vaccine, but also for individuals who suffer from a fear of needles. In fact, the university states that this approach is "set to be a gamechanger" for those who are needle-phobic. Professor Suresh Mahalingam, from Griffith's Institute for Biomedicine and Glycomics, has been leading the research for the past four years.

According to Mahalingam, the nasal vaccine has been specifically designed to be a single dose, making it an ideal booster vaccine. It also offers a safe alternative to needles, with no reported adverse reactions in the short or long term. Lead author Dr Xiang Liu adds that the vaccine provides cross-protection against all variants of concern, making it an even more promising option.

"The vaccine offers potent protection against transmission, prevents reinfection and the spread of the virus, while also reducing the generation of new variants," says Dr Liu. Unlike other vaccines that only target the spike protein, this nasal vaccine, called CDO-7N-1, induces immunity to all major SARS-CoV-2 proteins and has shown high effectiveness against all major variants to date.

One of the most significant advantages of this nasal vaccine is its stability. It can be stored at four degrees for up to seven months, making it an ideal option for low- and middle-income countries. This stability has also caught the attention of Indian Immunologicals Ltd, a major vaccine manufacturer, who has licensed the nasal vaccine.

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